Faculty Profile | Jessica Faulkner, PhD
Jessica Faulkner, PhD
About Jessica Faulkner, PhD
Studies in the Faulkner laboratory explore the mechanisms of high blood pressure, metabolic dysfunction, renal and vascular damage and fetal growth restriction in obese and lean pregnancy. In particular, the laboratory focuses on the physiological alterations to the vasculature caused by abnormal hormone release and activity in the vasculature, placenta, adrenal gland and adipose tissue utilizing human tissues/cell lines and rodent models of preeclampsia. The laboratory is primarily exploring mechanisms of metabolic dysfunction, vascular endothelial cell biology and function, renal injury, lipid dysfunction, uterine artery blood flow, steroid hormone synthesis, leptin and vascular endothelial growth factor signaling. Studies are approached with a translational perspective, utilizing transgenic and surgical mouse models as well as human tissues/cell lines to determine pathways involved in adverse outcomes of pregnancy in both mother and offspring in pregnancy. These results lead to mechanistic exploration of the underlying biochemical, molecular and genetic factors involved. Experiments to test our hypotheses include functional measures of blood pressure and vascular function, protein and mRNA expression measures as well as hormone, cell signaling and genetic analyses, among others. We approach all studies with translation and bench to bedside approach at the forefront. These studies are supported by ongoing grants from the NIH NHLBI, NIH NIDDK and the American Heart Association.Research Focus
My research program investigates the development of adverse pregnancy outcomes such as preeclampsia, gestational diabetes and fetal growth restriction utilizing animal models and clinical sample analysis. We use biochemical, molecular, genetic and endocrinological analyses to assess how certain factors lead to pregnancy disease.
Academic Focus
- Cardiovascular Physiology and Pharmacology
- Pregnancy and Reproduction
- Endocrinology
- Grant Writing
Education & Credentials
Laboratory Info
Lab Location
CA-3132E
Publications
Pure Publications
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Ives, M., Cooper, G., Bickerstaff, C., Elgazzaz, M., Sam, C., Brawley, A., Ogbi, S., Mellott, E., Moronge, D., Stokes, S., Hitchings, J., Zarate, L. V., , , & , Jul 2026, In: American Journal of Physiology - Endocrinology and Metabolism. 331, 1, p. E87-E97 Research output: Contribution to journal › Article › peer-review |
Mellott, E., Moronge, D., Cooper, G., Backer, K., Connor, G., Elgazzaz, M., Ogbi, S. & , Feb 2026, In: American Journal of Physiology - Heart and Circulatory Physiology. 330, 2, p. H581-H593 Research output: Contribution to journal › Article › peer-review |
Rodrigues, S. G., Assis, K. A., Silva, J. L. M., Privado, D. J. T., Alves, J. V., , Bruder-Nascimento, T. & Costa, R. M., Feb 2026, In: Comprehensive Physiology. 16, 1, e70107. Research output: Contribution to journal › Review article › peer-review |
Barris, C. T., Kress, T. C., Antonova, G., Jordan, C. R., Newman, A., , Saeed, M. I., Kennard, S. & , Dec 2025, In: American Journal of Physiology - Heart and Circulatory Physiology. 329, 6, p. H1526-H1535 Research output: Contribution to journal › Article › peer-review |
Elgazzaz, M., Brawley, A., Moronge, D. & , May 1 2025, In: Arteriosclerosis, thrombosis, and vascular biology. 45, 5, p. 585-599 15 p. Research output: Contribution to journal › Review article › peer-review |
, Apr 2025, In: Physiological Genomics. 57, 4, p. 254-255 2 p. Research output: Contribution to journal › Editorial › peer-review |
, , , , Taylor, E. B., , Ryan, M. J. & , Feb 2025, In: American Journal of Physiology - Renal Physiology. 328, 2, p. F204-F217 Research output: Contribution to journal › Review article › peer-review |
Moronge, D., Godley, H., Ayulo, V., Mellott, E., Elgazzaz, M., Cooper, G., , Ogbi, S., Gillis, E., & , Feb 2025, In: Clinical Science. 139, 4, p. 309-323 15 p. Research output: Contribution to journal › Article › peer-review |
& Alexander, M. R., Jan 17 2025, In: Circulation research. 136, 2, p. 191-193 3 p. Research output: Contribution to journal › Editorial › peer-review |
Shulha, A. S., Shyshenko, V., Schibalski, R. S., Jones, A. C., , Stadler, K. & , Dec 2024, In: Biochemical Society Transactions. 52, 6, p. 2307-2319 13 p. Research output: Contribution to journal › Review article › peer-review |
, Takano, M., Ogbi, S., Tong, W., Nakata, M., Moronge, D., Cindrova-Davies, T. & Giussani, D. A., Dec 2024, In: Placenta. 158, p. 253-262 10 p. Research output: Contribution to journal › Article › peer-review |
Hartman-Houstman, H. L., Ralph, D. L., Nelson, J. W., Palmer, L. G., , , Moronge, D. M. & McDonough, A. A., Oct 2024, In: American Journal of Physiology - Renal Physiology. 327, 4, p. F655-F666 Research output: Contribution to journal › Article › peer-review |
Ryan, M. J., Clemmer, J. S., Mathew, R. O., , Taylor, E. B., , Hollis, F. & , Sep 3 2024, In: Journal of Clinical Investigation. 134, 17, e180078. Research output: Contribution to journal › Review article › peer-review |
Elgazzaz, M., , & , Aug 2024, In: American Journal of Physiology - Cell Physiology. 327, 3, p. C646-C660 Research output: Contribution to journal › Review article › peer-review |
Moronge, D., Ayulo, V., Elgazzaz, M., Mellott, E., Ogbi, S. & , May 2024, In: American Journal of Physiology - Heart and Circulatory Physiology. 327, 1, p. H118-H130 Research output: Contribution to journal › Article › peer-review |
Warthi, G., , Doja, J., Ghanam, A. R., Gao, P., Yang, A. C., Slivano, O. J., Barris, C. T., Kress, T. C., Zawieja, S. D., Griffin, S. H., , Ashworth, A., Christie, C. K., , Kumar, A., Davis, M. J., , & & 2 others, , Jul 2023, In: Nature Cardiovascular Research. 2, 7, p. 702 1 p. Research output: Contribution to journal › Comment/debate › peer-review |
Moronge, D., & , Jul 2023, In: Comprehensive Physiology. 13, 3, p. 4869-4878 10 p. Research output: Contribution to journal › Article › peer-review |
Mellott, E. & , Mar 1 2023, In: Current opinion in nephrology and hypertension. 32, 2, p. 118-123 6 p. Research output: Contribution to journal › Review article › peer-review |
Barris, C. T., & , Feb 1 2023, In: Hypertension. 80, 2, p. 268-278 11 p. Research output: Contribution to journal › Review article › peer-review |
Warthi, G., , Doja, J., Ghanam, A. R., Gao, P., Yang, A. C., Slivano, O. J., Barris, C. T., Kress, T. C., Zawieja, S. D., Griffin, S. H., , Ashworth, A., Christie, C. K., , Kumar, A., Davis, M. J., , & & 2 others, , Nov 2022, In: Nature Cardiovascular Research. 1, 11, p. 1084-1100 17 p. Research output: Contribution to journal › Article › peer-review |
Atawia, R. T., , Mehta, V., Austin, A., Jordan, C. R., Kennard, S. & , Oct 2022, In: Vascular Pharmacology. 146, p. 107093 107093. Research output: Contribution to journal › Article › peer-review |
& , Sep 2022, In: Clinical Science. 136, 18, p. 1341-1346 6 p. Research output: Contribution to journal › Review article › peer-review |
, Wright, D., Antonova, G., Jaffe, I. Z., Kennard, S. & , Jul 1 2022, In: Hypertension. 79, 7, p. 1536-1547 12 p. Research output: Contribution to journal › Article › peer-review |
, Jun 2021, In: Clinical Science. 135, 12, p. 1523-1544 22 p. Research output: Contribution to journal › Review article › peer-review |
, Harwood, D., Kennard, S., Antonova, G., Clere, N. & , Jan 2021, In: American Journal of Physiology - Heart and Circulatory Physiology. 320, 1, p. H211-H220 Research output: Contribution to journal › Article › peer-review |
, Lluch, E., Kennard, S., Antonova, G., Jaffe, I. Z. & , Dec 2020, In: Biology of Sex Differences. 11, 1, 64. Research output: Contribution to journal › Article › peer-review |
& , Dec 1 2020, In: Current Hypertension Reports. 22, 12, 99. Research output: Contribution to journal › Review article › peer-review |
Elfarra, J. T., Cottrell, J. N., Cornelius, D. C., Cunningham, M. W., , Ibrahim, T., Lamarca, B. & Amaral, L. M., Jan 2020, In: Pregnancy Hypertension. 19, p. 226-232 7 p. Research output: Contribution to journal › Article › peer-review |
Bruder-Nascimento, T., , Haigh, S., Kennard, S., Antonova, G., , , & , Dec 1 2019, In: Hypertension. 74, 6, p. 1399-1408 10 p. Research output: Contribution to journal › Article › peer-review |
& , Oct 1 2019, In: Current Hypertension Reports. 21, 10, 78. Research output: Contribution to journal › Review article › peer-review |
, Kennard, S., Huby, A. C., Antonova, G., Lu, Q., Jaffe, I. Z., , & , Sep 1 2019, In: Hypertension. 74, 3, p. 678-686 9 p. Research output: Contribution to journal › Article › peer-review |
& , Jul 1 2019, In: Biology of Sex Differences. 10, 1, 30. Research output: Contribution to journal › Review article › peer-review |
Clemmer, J. S., , Mullen, A. J., Butler, K. R. & Hester, R. L., May 9 2019, In: Biology of Sex Differences. 10, 1, 24. Research output: Contribution to journal › Article › peer-review |
, , , Dan Rudic, R. & Bergson, C., Feb 2019, In: PloS one. 14, 2, e0211903. Research output: Contribution to journal › Article › peer-review |
& , Jan 1 2019, Aldosterone. Litwack, G. (ed.). Academic Press Inc., p. 265-284 20 p. (Vitamins and Hormones; vol. 109). Research output: Chapter in Book/Report/Conference proceeding › Chapter |
, Harwood, D., Bender, L., Shrestha, L., , Jane Morwitzer, M., Kennard, S., Antonova, G. & , Dec 2018, In: Hypertension. 72, 6, p. 1397-1406 10 p. Research output: Contribution to journal › Article › peer-review |
Lin, H. P., Singla, B., Ghoshal, P., , Cherian-Shaw, M., , She, J. X., & , Sep 2018, In: British Journal of Pharmacology. 175, 18, p. 3640-3655 16 p. Research output: Contribution to journal › Article › peer-review |
Plenty, N. L., , Cotton, J., Spencer, S. K., Wallace, K., LaMarca, B. & Murphy, S. R., May 2018, In: Prostaglandins and Other Lipid Mediators. 136, p. 15-22 8 p. Research output: Contribution to journal › Article › peer-review |
, Bruder-Nascimento, T. & , Mar 1 2018, In: Current opinion in nephrology and hypertension. 27, 2, p. 63-69 7 p. Research output: Contribution to journal › Review article › peer-review |
, Plenty, N. L., Wallace, K., Amaral, L. M., Cunningham, M. W., Murphy, S. & LaMarca, B., Jan 2018, In: Prostaglandins and Other Lipid Mediators. 134, p. 108-113 6 p. Research output: Contribution to journal › Article › peer-review |
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.Lab Members
Safia Ogbi
- Research Manager
Logan Baker
- Research Assistant
Mona Elgazzaz, PhD
- Postdoctoral Fellow
Amber Ajamu Johnson
- Graduate Student
Elisabeth Mellott, PhD
- Postdoctoral Fellow
Amalia Brawley, MD
- Maternal Fetal Medicine Fellow
Anxhela Treska, MD
- Maternal Fetal Medicine Fellow
Lab Spotlights
- American Heart Association Postdoctoral Fellowships
2024-2026 Mona Elgazzaz, MD, PhD
- American Society of Nephrology Predoctoral Fellowships
2024 Desmond Moronge, PhD
Other Accomplishments:
- Mona Elgazzazz, PhD, MD, Â鶹AV Dean's Travel Award recipient 2025, APS Cardiovascular Section Research Recognition Award, APS Summit 2025, Society for Reproductive Investigation President's Presenter Award 2025, Council on Hypertension New Investigator Travel Award, 2024 Scientific Sessions
- Elisabeth Mellott, AHA Council on Hypertension Onsite Poster Presentation Award 2025, 2nd place, Â鶹AV 3 minute Thesis Competition, AHA New Investigator Travel Award (Council on Hypertension Scientific Sessions 2022)
- Desmond Moronge, PhD AHA Council on Hypertension Trainee Advocacy Poster Award 2023, APS Renal Section Steven M. Horvath Professional Opportunity Award (APS Summit 2023), AU Graduate School Excellence in Research in Physiology 2023, AHA Award for Underrepresented Minorities (Council on Hypertension Scientific Sessions 2022), AU Graduate School Viranda Mahesh Award for Excellence in Endocrinology 2022, APS Martin Frank Minority Travel award (APS Control of Renal Function in Health and Disease Conference, 2022)
- Madison Ives, APS Physiological Reports Award, APS Summit 2024, Winner of best Presentation for "bench Bedside", MCG/Georgia Southern Joint research Conference, Savannah, GA 2024