Neurosurgery Research and Publications
Our research program aims to identify prevention measures and effective treatments for patients with neurological disorders. Our research is divided into various subspecialties, such as Cerebral Hemorrhage, Movement Disorders, Neuroprotection & Inflammation, Epilepsy, Gamma Knife Radiosurgery, Neuro-Oncology, Vascular Malformations, Degenerative Spine Disorders, Pediatric conditions and Traumatic Brain Injury (TBI). A strong collaboration between Basic Neuroscientists and Clinical Neurosurgeons is critical to the success of our mission.
Patients with specific neurosurgical conditions, who meet study-specific criteria, are invited to participate in our clinical research studies. Our clinical research activities are coordinated by a dedicated team of trained research coordinators, advanced practice providers, nurses, and therapists. Our research faculty have subspecialty training that includes research methodology, and all research is conducted under the oversight of Central and Local Institutional Review Boards. Our research funding is derived from a combination of medical industry sponsors and the National Institute of Health.
We offer a wide variety of research opportunities with our largest research projects reaching an international level and including dozens of qualified medical centers. In addition to large, multicenter clinical research, we also conduct many smaller scale investigations that involve our medical students, neurology and neurosurgery trainees.
These smaller local projects introduce future physicians to research methodology as well as the essential elements of the ethical and scientific standards associated with Good Clinical Practice in human research. The findings from our local research are presented at regional and national scientific meetings.
As a research unit, we strive to make scientific discoveries to improve the healthcare of patients with acute and chronic neurological conditions.
Current Research Topics
Faculty
Hyunwoo Do, MD
Fernando L. Vale, MD
Neurosurgery, Epilepsy Surgery, Deep Brain Stimulation, Low-grade gliomas
M. Salman Ali, MD
Skull Base, Pituitary Surgery
Scott Y. Rahimi, MD
Samuel D. Macomson, MD
Khoi Nguyen, MD
Alexander Post, MD
John R. Vender, MD
Research Labs
Krishnan Dhandapani, PhD
Molly Braun, PhD
Glymphatic System, Neuroimmunology, Traumatic Brain Injury, Neurodegeneration, Alzheimer's Disease
Kumar Vaibhav, PhD
Darrell W. Brann, PhD
Yujiao Lu, PhD
Julia V. Fomitcheva, PhD
Shannon Derthick, MSc
Residents
William 'Luke', Ledford, MD
PGY-1
Christopher Carr, MD, MPH
PGY-5
Luca Debs, MD
PGY-7
Recent Publications
Neurosurgery Research Publications
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Chauhan, A., Lee, E. A., Patel, R. B., Kumskova, M., Leira, E. C., Chauhan, A. K., Shi, Y., Cao, S., Koehler, R. C., , , , , , Herman, A. L., Boisserand, L., Sansing, L. H., Morais, A., Jin, X. & Aykan, S. & 8 others, , Mar 1 2026, In: Neuropharmacology. 285, 110801. Research output: Contribution to journal › Article › peer-review |
Arjipour, M., Rezaei, M., Yeganeh, S. A., Sabahi, M., Irani, A. D. & , Jan 2026, In: World Neurosurgery: X. 29, 100551. Research output: Contribution to journal › Review article › peer-review |
Gaur, P., Ahluwalia, M., Ahluwalia, P. & , Dec 2025, In: Biomedicines. 13, 12, 3096. Research output: Contribution to journal › Editorial › peer-review |
Boisserand, L. S. B., Herman, A. L., Sanganahalli, B. G., Mihailovic, J., Beatty, H. E., Johnson, C. W., Diaz, S., DeLong, J. H., Velazquez, S., Grutzendler, J., Dela Cruz, C., Zhou, J., Sheth, K. N., Matouk, C., Zhan, S., Morais, A., Imai, T., Chauhan, A., Patel, R. B. & Kumskova, M. & 19 others, , Nov 18 2025, In: Stroke. 56, 11, p. 3280-3293 14 p. Research output: Contribution to journal › Article › peer-review |
Debs, L. H., & , Oct 2025, In: Neurosurgical focus. 59, 4, E10. Research output: Contribution to journal › Article › peer-review |
behalf of the SPAN investigators, Sep 25 2025, In: Journal of the American Heart Association. 14, 19, e040914. Research output: Contribution to journal › Article › peer-review |
Jin, X., Morais, A., Imai, T., Lamb, J., Nagarkatti, K., Boisserand, L., Beatty, H. E., Sansing, L. H., , , , , Patel, R. B., Kumskova, M., Chauhan, A. K., McCullough, L. D., Aronowski, J., Leira, E. C., Shi, Y. & Avery, B. D. & 3 others, , Sep 2025, In: Stroke. 56, 9, p. 2734-2747 14 p. Research output: Contribution to journal › Article › peer-review |
Butler, M., Kaoutzani, L. & , Jul 2025, In: World Neurosurgery. 199, 124159. Research output: Contribution to journal › Article › peer-review |
Gandhi, D., Chen, H., Zaidi, S., Sahlein, D. H., Maidan, L., Kreitel, K., Miller, T. R., , Shekhlee, A. A., Woo, H. H., Toth, G., Schirmer, C., Loh, Y. & Fiorella, D., Jul 1 2025, In: Journal of NeuroInterventional Surgery. 17, 7, p. 753-758 6 p. Research output: Contribution to journal › Article › peer-review |
, , Siddiqui, S., Williams, D., , Naeini, S. E., , , , & , Apr 2025, In: Translational Stroke Research. 16, 2, p. 421-437 17 p., e571. Research output: Contribution to journal › Article › peer-review |
Patel, R. B., Kumskova, M., Kodali, H., Budnik, I., Kuznetsov, V., Jain, A., Jha, A., Thedens, D., Dhanesha, N., Sutariya, B., Nagarkatti, K. A., Lamb, J., , Shi, Y., Avery, B., Imai, T., Jin, X., Chauhan, A., Boisserand, L. S. B. & & 14 others, , Apr 1 2025, In: Stroke. 56, 4, p. 965-973 9 p. Research output: Contribution to journal › Article › peer-review |
, , Siddiqui, S., Hattaway, T. G., Anas, A., , , & , Feb 2025, In: Experimental Neurology. 384, 115067. Research output: Contribution to journal › Article › peer-review |
Bhandari, B., Naeini, S. E., Rezaee, S., Rogers, H. M., Khodadadi, H., , Seyyedi, M., MacKinnon, N. J., , , , Yu, J. C., , , Wang, L. P. & , Jan 1 2025, In: Translational Neuroscience. 16, 1, 20220362. Research output: Contribution to journal › Article › peer-review |
Sellers, H. G., Brown, Z. L., Khalil, N. S., Haigh, S. B., Shivers, M. A., Patel, T. V., Joshua, A. T., , , , , & , 2025, (Accepted/In press) In: Obesity. Research output: Contribution to journal › Article › peer-review |
Alptekin, A., , Parvin, M., Chowdhury, H., Kashif, S., Selina, F. A., Bushra, A., Kelleher, J., , Williams, D., Blumling, E., Ara, R., , Frank, J. A., & , 2025, In: Frontiers in Neurology. 16, 1543133. Research output: Contribution to journal › Article › peer-review |
Sword, J., Fomitcheva, I. V. & , Dec 2024, In: Journal of Cerebral Blood Flow and Metabolism. 44, 12, p. 1561-1579 19 p. Research output: Contribution to journal › Article › peer-review |
Debs, L. H., Walker, S. E. & , Dec 2024, In: GeroScience. 46, 6, p. 6537-6561 25 p. Research output: Contribution to journal › Review article › peer-review |
Peterson, D., Van Poppel, M., Boling, W., Santos, P., Schwalb, J., Eisenberg, H., Mehta, A., Spader, H., Botros, J., Vrionis, F. D., Ko, A., Adelson, P. D., Lega, B., Konrad, P., Calle, G., , Bucholz, R. & Richardson, R. M., Dec 2024, In: Bioelectronic Medicine. 10, 1, 8. Research output: Contribution to journal › Article › peer-review |
, Gulhane, M., Ahluwalia, P., Kumar, M., Ahluwalia, M., Rafiq, A. M., Amble, V., Zabala, M. G., Miller, J. B., Goldman, L., , , , & , Dec 2024, In: GeroScience. 46, 6, p. 5439-5457 19 p. Research output: Contribution to journal › Article › peer-review |
Kolls, B. J., Muir, K. W., Savitz, S. I., Wechsler, L. R., Pilitsis, J. G., , Beckman, R. L., Holmes, V., Chen, P. R., Albers, D. S. & Laskowitz, D. T., Dec 2024, In: Trials. 25, 1, 150. Research output: Contribution to journal › Article › peer-review |
Khodadadi, H., , Naeini, S. E., Bhandari, B., Rogers, H. M., Gouron, J., Meeks, W., , Pillai, A., Yu, J. C., Morgan, J. C., , , , Wang, L. P. & , Nov 2024, In: International journal of molecular sciences. 25, 21, 11764. Research output: Contribution to journal › Article › peer-review |
Debs, L. H., , Walker, S., Toro, D., Mansouri, S., & , Oct 2024, In: Journal of Clinical Neuroscience. 128, 110783. Research output: Contribution to journal › Article › peer-review |
Rashidi, F., Habibi, M. A., Reyhani, M., Fallahi, M. S., Arshadi, M. R., Sabahi, M., Vakharia, K. & , Sep 2024, In: World Neurosurgery. 189, p. 399-409.e18 Research output: Contribution to journal › Review article › peer-review |
Morais, A., Imai, T., Jin, X., Locascio, J. J., Boisserand, L., Herman, A. L., Chauhan, A., Lamb, J., Nagarkatti, K., Diniz, M. A., Kumskova, M., Dhanesha, N., , , , Patel, R. B., Sutariya, B., Shi, Y., van Leyen, K. & Kimberly, W. T. & 8 others, , Aug 16 2024, In: Circulation research. 135, 5, p. 575-592 18 p. Research output: Contribution to journal › Article › peer-review |
Jones, E. D., Kaoutzani, L., Walker, S. E., Kollapaneni, S. S., & , Aug 2024, In: World Neurosurgery. 188, p. e491-e496 Research output: Contribution to journal › Article › peer-review |
, & Howington, Z., Jul 1 2024, In: Nursing Education Perspectives. 45, 4, p. 254-255 2 p. Research output: Contribution to journal › Article › peer-review |
Wang, L. P., Chagas, P. S., , Naeini, S. E., Gouron, J., Rogers, H. M., Khodadadi, H., Bhandari, B., Alptekin, A., Qin, X., , Costigliola, V., , , , Rutkowski, M., Yu, J. C. & , Jun 2024, In: Medical Oncology. 41, 6, 140. Research output: Contribution to journal › Article › peer-review |
Kaoutzani, L., & , May 1 2024, In: Journal of Surgical Case Reports. 2024, 5, rjae331. Research output: Contribution to journal › Article › peer-review |
Oliver, T., Kelly, A. & , Apr 1 2024, In: Operative Neurosurgery. 26, 4, p. 472-473 2 p. Research output: Contribution to journal › Article › peer-review |
, MacDonald, T. J., , Aguilera, D., Al-Basheer, A., Bajaj, M., Bandopadhayay, P., , Bouffet, E., Castellino, R. C., Dorris, K., Eaton, B. R., Esiashvili, N., Fangusaro, J. R., Foreman, N., Fridlyand, D., Giller, C., Heger, I. M., Huang, C. & Kadom, N. & 18 others, , Feb 1 2024, In: Neuro-Oncology. 26, 2, p. 348-361 14 p. Research output: Contribution to journal › Article › peer-review |
Ahluwalia, P., Ballur, K., Leeman, T., Vashisht, A., Singh, H., Omar, N., , , & , Feb 2024, In: Cancers. 16, 3, 480. Research output: Contribution to journal › Review article › peer-review |
Goldman, L., Espinosa, M. P., Kumar, M., Debs, L. H., & , Jan 1 2024, Mechanism and Genetic Susceptibility of Neurological Disorders. Springer Science+Business Media, p. 35-57 23 p. Research output: Chapter in Book/Report/Conference proceeding › Chapter |
Neal, E. G., Schimmel, S., George, Z., Monsour, M., Alayli, A., Lockard, G., Piper, K., Maciver, S., & Bezchlibnyk, Y. B., 2024, In: Frontiers in Network Physiology. 4, 1342161. Research output: Contribution to journal › Article › peer-review |
Kaoutzani, L., Goldman, L. V., Piper, K., Kumar, M. & , Dec 2023, In: Acta Neurochirurgica. 165, 12, p. 3913-3920 8 p. Research output: Contribution to journal › Article › peer-review |
Youngerman, B. E., Banu, M. A., Khan, F., McKhann, G. M., Schevon, C. A., Jagid, J. R., Cajigas, I., Theodotou, C. B., Ko, A., Buckley, R., Ojemann, J. G., Miller, J. W., Laxton, A. W., Couture, D. E., Popli, G. S., Buch, V. P., Halpern, C. H., Le, S., Sharan, A. D. & Sperling, M. R. & 12 others, , Nov 1 2023, In: Journal of Neurology, Neurosurgery and Psychiatry. 94, 11, p. 879-886 8 p. Research output: Contribution to journal › Article › peer-review |
Khodadadi, H., , Alptekin, A., Mehrabian, D., Rutkowski, M., , , Yu, J. C., Morgan, J. C., , , & , Oct 1 2023, In: Cannabis and Cannabinoid Research. 8, 5, p. 824-834 11 p. Research output: Contribution to journal › Article › peer-review |
Lyden, P. D., Diniz, M. A., Bosetti, F., Lamb, J., Nagarkatti, K. A., Rogatko, A., Kim, S., Cabeen, R. P., Koenig, J. I., Akhter, K., , Avery, B. D., Beatty, H. E., Bibic, A., Cao, S., Boisserand, L. S. B., Chamorro, A., Chauhan, A., Diaz-Perez, S. & & 29 others, , Sep 20 2023, In: Science Translational Medicine. 15, 714, eadg8656. Research output: Contribution to journal › Article › peer-review |
Debs, L. H., Helton, A., Belakhlef, S., Sharma, S. & , Aug 29 2023, In: Neurology. 101, 9, p. E982-E983 Research output: Contribution to journal › Article › peer-review |
Sellers, H. G., Padgett, C. A., Mintz, J. D., Speese, A. C., Brown, Z. L., Haigh, S., Sword, J., Rosewater, C. L., Shivers, M. A., Barris, C. T., , , , & , Aug 1 2023, In: Arteriosclerosis, thrombosis, and vascular biology. 43, 8, p. 1592-1594 3 p. Research output: Contribution to journal › Article › peer-review |
Ahluwalia, M., Gaur, P. & , Jul 2023, In: Biomedicines. 11, 7, 1947. Research output: Contribution to journal › Editorial › peer-review |
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